一、尝试修复Python环境
1、sudo apt install -f 修复下
2、sudo apt reinstall deepin-wine-builder deepin-wine10-stable python3-yaml python3-pycurl python3-chardet python3-requests patool python3-urllib3 python3-certifi python3-pefile python3-xdg python3-dbus python3-watchdog 重装下

执行完再试试

二、还是不行看下日志
执行 /opt/apps/deepin-wine-builder/files/share/deepin-wine-builder/service/service.py 看看是否有报错

也看下这个日志 ~/.local/share/deepin-wine-bottles/bottles.log